7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3- carboxylic acid compounds useful as antibacterial agents

Abstract From the Canadian patent

7-Substituted-6-fluor-1,4-dihydro-4-oxo-quinolinenaphthyridine- and , benzoxazine carboxylic acids of formula (1) wher-, ein R1 is a cycloalkyl group or a phenyl group which may be substituted by one or two halogen atoms; R2 is hydrogen, a halogen atom, an alkyl group, a hydroxy group or an amino group; R3 is hydrogen hydroxy or amino; R4 is a 1,2,3-triazol- 1-yl group, a 1,2,4-triazol-1-yl group a 1,2,3,4-tetrazol-1-yl or a 1,2,3,4-, tetrazol-2-yl group each of which may have 1 to 2, substituents selected from the group consisting of alkyl COOH, CH2NH2, amino , and phenyl groups; and x is N CH, C-F, or C-OCH3; n is 0, 1 or 2; or (II) may be (III) are described, as well as a , process for …