Novel estradiol derivative-chlorabucil conjugate, process for preparing the same, and pharmaceutical compositions
CA 2097137 A1 · Owner: Matsudaira, Tadahiro · Inventors: Mitsuhashi, Satoshi; Matsudaira, Tadahiro; Tamura, Fumio
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
An estradiol derivative-chlorambucil conjugate of the formula (I):, (I), wherein R1 is alkyl or alkoxyl of 1 to 4 carbon atoms; R2 is acyl, dansyl, or alkyl; R3, R4, and R5 independently are H oxo, OH, or acyloxy; m is an integer of 1 to 3; and n is an integer of 0 to 3; provided that when n is 0, all of R3 R4, and R5 are, not H at the same time and at least one of R3, R4, and R5 is a group other than H and OH; and further when n is 2 or 3, the, groups R1 are the same or different; a process for preparing the same, and a pharmaceutical composition containing the conjugate are described.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 27, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 27, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 27, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.