Drug delivery porphyrin compositions and methods
CA 2096841 C · Owner: Kahl, Stephen B. · Inventors: Kahl, Stephen B.; Koo, Myoung-Seo
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A compound is described having structure (I) where R preferably is (a) and most preferably R3 is a closo-carborane and R2 is H, an alkyl or aryl having 1 to about 7 carbon atoms or a , physiologically acceptable salt. Compounds of the invention are useful in boron neutron capture therapy; photodynamic therapy and other , biomedical applications. One embodiment we have designated 2,4-bis-.alpha. .beta.-(1,2-dicarbaclosododecaborane carboxy)ethyldeuteroporphyrin (x), appears not to pass through the normal blood brain barrier has excellent water solubility, and , has been shown efficacious in boron neutron capture therapy in vivo against the KHJJ mammary carcinoma:
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 19, 1991 and granted September 3, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended November 19, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 19, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.