Composition and method
CA 2095569 A1 · Owner: Boyd, Samantha J. · Inventors: Boyd, Samantha J.; Butler, Sidney P.; Parkes, Sharon L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a radiolabelled t-PA having substantially all plasminogen catalytic sites inactivated and which is able to bind to a thrombus and/or fibrin. It also provides a composition for localising deep venous thrombosis using the compound of this invention, together with a pharmaceutically acceptable carrier diluent, and/or excipient. The invention also provides a process for preparing the compound of this invention, which process comprises reacting t-PA with an agent to inactivate the plasminogen catalytic site followed by cleaving disulfide bridges in the t-PA and labelling the thus-reduced t-PA. The invention specifically provides for the use of recombinant t-PA …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 5, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 5, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 5, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.