Methods for the use of spermidine/spermine n1-acetyltransferase as a prognostic indicator and/or tumor response marker
CA 2094341 A1 · Owner: Porter, Carl W. · Inventors: Porter, Carl W.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed is a method that relates to the measurement of determinants related to the in-vivo induction of spermidine/ spermine Nl-acetyltransferase (SSAT), subsequent to treatment with polyamine analogs that induce SSAT such as bis-ethyl spermine analogs, in tumor types responsive to this class of analogs. The method comprises the measurement of one or more SSAT-specific determinants that include SSAT enzyme activity SSAT enzyme, protein, and SSAT m-RNA transcripts. Alternatively other, determinants related to the SSAT induction may be measured. Such determinants include SSAT co-factor acetylCoenzyme A and SSAT, products Nl-acetylspermidineand Nl-acetylspermine. Measurements of these …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 19, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 19, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 19, 2015.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.