Stable isoforms of creatine kinase for standard markers and diagnosis
CA 2094221 A1 · Owner: Kesterson, Robert · Inventors: Friedman, David L.; Roberts, Robert; Perryman, M. Benjamin
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to stable isoforms of creatine kinase (CK) subunits. Recombinant subunits may be expressed in cells cotransfected with DNA encoding one or more wild-type creatine kinase subunit B, wild-type subunit M or mutant M CK subunits. The subunits and dimeric species produced by association of the monomeric units are indistinguishable in electrophoretic mobility from creatine isoforms produced in vivo. The various isoforms are useful as analytical standards in commonly used tests to determine the presence of creatine isoforms. The disclosed isoforms have good storage stability and are stable under conditions employed for nondenaturing electrophoresis.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 16, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 16, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 16, 2015.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.