Pyrimidine derivatives and processes for the preparation thereof

Abstract From the Canadian patent

There are described N-phenyl-2-pyrimidine-amine derivatives of formula I wherein, R1 is pyrazinyl, 1-methyl-1H pyrrolyl amino- or amino-lower alkyl-substituted phenyl wherein the amino group in each cast is free alkylated or acylated, 1H-indolyl or 1H-imidazolyl bonded at a five-membered ring carbon atom or, unsubstitut ed or lower alkyl-substituted pyridyl bonded at a ring carbon atom and, unsubstituted or substituted at the nitrogen atom by oxygen R2 and R3 are each independently of the other hydrogen or lower alkyl one or two of the radicals R4, R5, R6, R7 and R8 are each nitro fluoro-, substituted lower , alkoxy or a radical of formula II -N(R9)-C(=X)-(Y)n-R10 (II), wherein, R9 is …