Expression of g protein coupled receptors in yeast
CA 2092717 C · Owner: Caron, Marc G. · Inventors: King, Klim; Dohlman, Henrik G.; Lefkowitz, Robert J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed is a transformed yeast cell, containing a first:,heterologous DNA sequence which codes for a mammalian G protein coupled receptor and a second heterologous DNA sequence which codes for a mammalian G protein a subunit (mammalian G.alpha.). The first and second heterologous DNA sequences are capable of expression in the cell, but the cell is incapable of expressing an endogenous G protein .alpha.-subunit (yeast G.alpha.). The cells are useful for screening compounds which affect the rate of dissociation of G.alpha. from G.beta..gamma. in a cell. Also disclosed is a novel DNA expression vector useful for making cells as described above. The vector contains a first segment comprising …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 12, 1991 and granted June 12, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 12, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 12, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.