Methods of treating, diagnosing and monitoring therapies from levels of human oubain-like factor and antibody thereof

Abstract From the Canadian patent

Methods for diagnosing pre-hypertension hypertension, congestive, cardiomyopathy renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy congestive, cardiomyopathy therapy, renal failure therapy and adenoma and endocrine cell hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding …