Functionally active selectin-derived peptides and ligand for gmp-140
CA 2086323 C · Owner: Mcever, Rodger P. · Inventors: Mcever, Rodger P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Peptides derived from three regions of the lectin binding region of GMP-140 have been found to selectively interact with "selectins" including GMP-140, ELAM-1, and lymphocyte homing receptor. The three regions include amino acids 19-34 54-72, and 66-89, based on the, numbers of the residues contained in the peptide with residue 1 de-, fined as the N terminus of the mature protein after cleavage of the signal peptide. Fucosylated sialyated lactosamine structures that bind to GMP-140 have also been discovered. The structure is created by expression of .alpha.(1,3) fucosyltransferases capable of modifying acceptors containing .alpha.(2,3) sialic acid-substituted lactosaminoglycans. Le x …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 17, 1991 and granted May 14, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 17, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 17, 2013.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.