"sequence-specific non-photoactivated crosslinking agents which bind to the major groove of duplex dna
CA 2083719 A1 · Owner: Krawczyk, Steven · Inventors: Krawczyk, Steven; Matteucci, Mark D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Agents which bind to the major groove of nucleic acid duplexes in a sequence-specific manner and are capable of forming covalent bonds with one or both strands of the duplex in the absence of light are useful therapeutic agents in the treatment of conditions mediated by duplex DNA. These agents are designed so that the reactivity of the crosslinking agent does not interfere with the sequence specificity of the agent which binds to the major groove. Thus specific desired DNA duplexes can be targeted and their activity diminished or enhanced.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 24, 1991. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 24, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 24, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.