Compositions and methods for modulating rna activity through modification of the 5' cap structure of rna
CA 2083377 C · Owner: Isis Pharmaceuticals, Inc. · Inventors: Baker, Brenda F.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods for achieving therapeutic treatment of diseases and for regulating gene expression in biological experimental systems via modification or removal of the 5' Cap stricture of targeted ribonucleic acids are disclosed. Modification or removal of the 5' Cap structure is achieved in accordance with preferred embodiments utilizing antisense compounds which are complementary to the 5' terminus of the targeted RNA and have attached to them reactive moieties explicitly designed for chemical modification of or cleavage reactions with the 5' Cap structure of RNA.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 22, 1991 and granted November 26, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 22, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 22, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.