Enzymatic neutralization of heparin
CA 2083162 C · Owner: Biomarin Enzymes Inc. · Inventors: Heft, Robert A.; Lewis, N. Tracey; Zimmermann, Joseph J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A heparinase formulation derived from F. heparinum which meets all requirements for a clinical reagent that can eliminate heparin interference of normal blood function has been developed. The heparinase derived from F. heparinum, is free of a component that inhibits coagulation. It is stable under normal manufacturing shipping and clinical storage conditions for a least one year. The heparinase is useful in vitro to eliminate the interference in hematological assays due to the presence of heparin. The heparinase is also useful for the in vivo neutralization of heparin during surgical procedures. Advantages of this preparation are that it achieves neutralization faster and more completely …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 3, 1992 and granted August 11, 1998. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 3, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 3, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.