Radioiodinated benzovesamicol analogs for cholinergic nerve mapping
CA 2082797 A1 · Owner: Wieland, Donald M. · Inventors: Gildersleeve, David L.; Van Dort, Marcian E.; Jung, Yong-Woon
Overview
Its claims, description and drawings are in the Canadian Patents Database.
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Radioiodinated benzovesamicol analogs which selectively localize in presynaptic cholinergic neurons of general formula (I) where , X is selected from the group consisting of H OH, NH2, NHCO-3-I-Ph, and a radioactive isotope of iodine and Y is selected, from the group of H and a radioactive isotope of iodine Y being H, if X contains iodine. Illustrative examples include: (±)-trans-2-hydroxy-5-iodo-3-(4-phenylpiperidino)tetralin; (±)-trans-3-hydroxy-5-iodo-2-(4-phenylpiperidino)tetralin; (±)-trans-5-amino-2-hydroxy-8-iodo-3-(4-phenylpiperidino)tetralin; and (±)-trans-2-hydroxy-5-(3-iodobenzamido)-3-(4-phenylpiperidino)tetralin. The novel radioiodinated benzovesamicol analogs may be used as …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 10, 1991. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 10, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 10, 2013.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.