Diastereoselective process for preparing n-substituted amino acids and derivatives
CA 2081316 A1 · Owner: Schering Corporation · Inventors: Gosteli, Jacques; Tanner, Markus; Mergelsberg, Ingrid
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for preparing an (S S) or (R, R) diastereoisomer of, formula (X) or salts esters or amides thereof, wherein R3 and R4 independently represent hydrogen, alkyl aryl or aryl, substituted with halogen alkyl, nitro or alkoxy, and n and m, independently represent integers from one to six comprising combining a, cyanide compound of the formula: M1C=N wherein M1 is hydrogen, trimethylsilyl or a metal with an optional proton source, a, solvent and a Lewis acid of the formula: M2X4 AlCl3 or BF3, wherein M2 is Sn or Ti and X represents chloro bromo, fluoro, or iodo, with an .alpha.-amino acid compound or salts or esters thereof, followed by addition of an acyl or acetal compound to give the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 29, 1991. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 29, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 29, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.