Chimeric antibodies with receptor binding ligands in place of their constant region
CA 2078689 C · Owner: Morrison, Sherie L. · Inventors: Shin, Seung-Uon; Morrison, Sherie L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a modified chimeric monoclonal antibody comprising wo molecules of each of two different polypeptides. The shorter polypeptides function as the light chains of the antibody and the longer polypeptides function as the heavy chains of the antibody. Moreover; the polypeptide which functions as a heavy chain has a variable region characteristic of a first mammal and a constant region characteristic of a second mammal. Each polypeptide which functions as a light chain has a variable region characteristic of a mammal and a constant region characteristic of a mammal; wherein a receptor-binding ligand replaces at least a portion of the constant region of each of …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 20, 1991 and granted February 11, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 20, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 20, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.