Biotin operon
CA 2078043 C · Owner: Shiseido Company Ltd. · Inventors: Haze, Shinitiro; Kishimoto, Jiro; Ifuku, Ohji
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A DNA sequence of a high biotin operon-expression system usable for breeding a bacterium having excellent biotin productivity is provided. The invention relates to a DNA sequence of the biotin operon characterized by having at least one base pair of either a nucleotide sequence of the regulatory region of the biotin operon of Escherichia coli or a nucleotide sequence in the vicinity of the bioB initiating codon which is mutated in comparison with the wild type strain. Escherichia coli transformed with a recombinant plasmid carrying such a DNA sequence has high biotin productivity.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 11, 1992 and granted May 20, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 11, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 11, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.