Method for enhancing antibody transport through capillary barriers
CA 2077670 C · Owner: The Regents Of The University Of California · Inventors: Pardridge, William M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for increasing the transcytosis of an antibody across the microvascular barrier and into the interstitial fluid of organs is disclosed. The method consists of cationizing the antibody with a cationizing agent to increase the isoelectric point of the antibody by between about 1 to about 7 to produce a cationized antibody having an isoelectric point which is less than about 11.5. The increased rate of transport across the microvascular barrier of organs makes such canonized antibodies useful for both therapeutic and diagnostic purposes.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 6, 1991 and granted October 1, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 6, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 6, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.