Recombinant antibodies specific for tnf-.alpha.
CA 2076540 C · Owner: Emtage, John Spencer · Inventors: Emtage, John Spencer; Adair, John Robert; Athwal, Diljeet Singh
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Recombinant, in particular humanised, e.g. humanised chimeric and CDR-grafted humanised, antibody molecules having, specificity fox human TNF.alpha. are provided for use in diagnosis and therapy. In particular the antibody molecules have antigen binding sites derived from murine monoclonal antibodies CB0006 CB0010, hTNF3 , or 101.4. Preferred CDR-grafted humanised anti-hTNF.alpha. antibodies comprise variable region domains comprising human acceptor framework and donor antigen binding regions and wherein the frameworks comprise donor residues at specific positions. The antibody molecules may be used for therapeutic treatment of human patients suffering from or at risk of disorders …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 20, 1991 and granted March 27, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 20, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 20, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.