Dna encoding precursor interleukin 1beta converting enzyme
CA 2076159 C · Owner: Merck & Co. Inc. · Inventors: Molineaux, Susan M.; Howard, Andrew D.; Tocci, Michael J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Complementary DNA (cDNA) encoding the, precursor interleukin-1.beta. (pre-IL-1.beta.) converting enzyme (ICE) is isolated from a cDNA library. A cDNA, encoding the full-length open reading frame (ORF) for the nascent ICE, as well as individual cDNAs encoding the 20 kDa subunit and the 10 kDa subunit of ICE are identified and sequenced. ICE is useful in the conversion of pre-IL-1.beta. into mature IL-1.beta.. The recombinantly produced ICE including the, individual 20 kDa and 10 kDa subunits is useful in the diagnosis of inflammatory diseases in the, production of recombinant IL-1.beta. and to identify inhibitors of ICE activity.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 14, 1992 and granted December 5, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 14, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 14, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.