Genetic engineering process for the production of s-(+)-2,2-dimethylcyclopropanecarboxamide by microorganisms
CA 2074681 C · Owner: Birch, Olwen M. · Inventors: Robins, Karen; Birch, Olwen M.; Bohlen, Elisabeth
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A genetic engineering process is disclosed for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide. For this purpose, a new DNA that codes for a stereospecific hydrolase is isolated from a microorganism. This DNA is then ligated in an expression vector, and a hybrid plasmid results which is used to transform microorganisms. These microorganisms are then able to biotransform the R-(-) isomer in racemic R,S-(~)-2,2-dimethylcyclopropanecarboxamide into R-(-)-2,2-dimethylcyclopropanecarboxylic acid. Optically active S-(-H)-2,2-dimethylcyclopropanecarboxamide is thus obtained.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 27, 1992 and granted November 28, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 27, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 27, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.