Carbostyril derivatives and their use

Abstract From the Canadian patent

Disclosed are carbostyril derivatives of the general formula, (see above formula), wherein, R1a is a halogen or a lower alkoxy lower alkyl, lower, alkenyloxy, amino, lower alkanoylamino or lower alkylthio group;, R2 is a phenyl group which optionally may have one or two substituents each independently selected from the group consisting of halogen, lower alkoxy, lower alkyl nitro, amino, lower alkanoylamino, hydroxyl cyano, phenyl-lower, alkoxy and halo-lower alkyl; A is a lower alkylene group; and, the carbon-carbon bond between the positions 3 and 4 of the carbostyril skeleton is a single bond or a double bond; and salts thereof, and pharmaceutical compositions containing the same, for use …