Therapeutic ribozyme compositions and expression vectors
CA 2066684 A1 · Owner: Robertson, Hugh D. · Inventors: Goldberg, Allan R.; George, Shaji T.; Robertson, Hugh D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Hepatitis delta is used as a vector for inhibition of viral infection and to express proteins in vivo in a cell-specific manner. The scope of delta's use as a vector is broadened in the present invention in several important ways. For example a delta RNA , genome capable of self-replication is enlarged to carry additional information, either coding for messenger RNA for a protein or , for a targeted ribozyme, which can be delivered to liver cells using delta's normally infectious properties or to other cell, types using chimeric delta viral agents carrying altered surface proteins. In another embodiment, the delta vector is made self-limiting, so that its role in delivering targeted …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 25, 1990. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 25, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 25, 2012.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.