Recombinant negative strand rna virus expression systems and vaccines
CA 2065245 C · Owner: Krystal, Mark · Inventors: Parvin, Jeffrey D.; Krystal, Mark; Palese, Peter
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Recombinant negative strand virus RNA templates which may be used to express heterologous gene products and/or to construct chimeric viruses are described. Influenza viral polymerase which was prepared depleted of, viral RNA was used to copy small RNA templates prepared from plasmid-encoded sequences. Template constructions containing only the 3' end of genomic RNA were shown to be efficiently copied, indicative that the promoter lay solely within the 15 nucleotide 3' terminus. Sequences not specific for the influenza viral termini were not copied and, surprisingly, RNAS containing termini identical to those from plus sense cRNA were copied at low levels. The specificity for recognition of …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 27, 1990 and granted November 12, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 27, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 27, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.