Inhibition of tumor growth by blockade of the protein c system
CA 2064585 C · Owner: Oklahoma Medical Research Foundation · Inventors: Esmon, Charles T.; Comp, Philip C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Composition, and methods of use thereof for the inhibition of tumor growth and killing of tumors having extensive microcirculation wherein the active agent is a compound blocking the protein C system preferably anti-protein C antibody, anti-protein S antibody and C4b binding protein. In the most preferred embodiment the protein C blocking compound is provided in combination with a cytokine such as tumor necrosis factor (TNF) gamma interferon, interleukin-1, interleukin-2 and granulo-cytemacrophage colony stimulating factor. Example are provided demonstrating the administration of the protein C blocking compound, alone or in combination with TNF to dogs having canine venereal tumors, a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 2, 1990 and granted April 27, 1999. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 2, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 2, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.