Biologically active polypeptides based on transformed growth factor-beta sequences
CA 2057896 C · Owner: Cianciolo, George J. · Inventors: Cianciolo, George J.; Burnier, John P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A polypeptide is provided that excludes (a) a full-length mature TGF-.beta. molecule or precursor TGF-.beta. molecule or deletion variants of mature or precursor TGF-.beta. molecules in which from about 1 to 10 amino acid residues have been deleted (b) a , poly-peptide of the sequence: Cys-Val-Arg-Gln-Leu-Tyr-Ile-Asp-Phe-Arg-Lys-Asp- Leu-Gly-Trp-Lys, and (c) a polypeptide of the sequence: Arg-Asn-Leu-Glu-Glu-Asn-Cys-Cys-Val-Arg-Pro-Leu-Tyr-Ile-Asp-Phe-Arg- Gln-Asp-Leu, said polypeptide comprising an amino acid sequence that is based on conserved sequences in the family of TGF-.beta. molecules. Such polypeptides are particularly useful therapeutically as immunosuppressive agents when …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 4, 1990 and granted June 6, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 4, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 4, 2012.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.