Accumulation of drugs into liposomes by a proton gradient
CA 2056435 A1 · Owner: Hope, Michael J. · Inventors: Harrigan, P. Richard; Bally, Marcel B.; Hope, Michael J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to pharmaceutical compositions and methods of making liposome containing compositions exhibiting characteristics of great uptake. This uptake may be greater than what would be expected by the relationship defined by the Henderson-Hasselbach equation. The present invention also relates to lipososmal compositions wherein the liposome comprises in part a membrane-stabilizing component, for example cholesterol, which, exhibits favorable characteristics in preventing rapid release of a pharmaceutical agent selected from the group consisting of quinine quinidine and diphenhydramine after it has been formulated in liposomes. The present invention also relates to …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 15, 1990. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 15, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 15, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.