Process and compositions for the isolation of human relaxin
CA 2051375 C · Owner: Genentech, Inc. · Inventors: Henner, Dennis J.; Vandlen, Richard L.; Wilkins, James A.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process is provided for cleaving a polypeptide into at lease two polypeptide components comprising treating a reduced free-cysteine form of the polypeptide with a cleaving agent under conditions for cleaving the polypeptide at a desired junction between the polypeptide cleavage products. More preferably the process for , cleaving comprises culturing cells containing DNA encoding said polypeptide, wherein at least one Asp codon is present in said DNA at a desired junction between the components to be cleaved from each other, said culturing resulting in expression of the DNA to produce the polypeptide in the host cell culture; and treating a reduced, free-cysteine form of the …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 16, 1990 and granted September 12, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 16, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 16, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.