Production in bacteria and yeast of hemoglobin and analogues thereof
CA 2050601 C · Owner: Nagai, Kiyoshi · Inventors: Nagai, Kiyoshi; Rosendal, Mary S.; Wagenbach, Michael
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Alpha subunits of hemoglobin are provided as a novel recombinant di-alpha globin polypeptide comprising the two alpha subunits connected directly via peptide bond or indirectly by a flexible aminoacid or peptide linker. Di-alpha globin may be combined in vivo or in vivo with beta globin and heme to form hemoglobin. Tetrameric human hemoglobin and di-alpha/beta 2 hemoglobin are produced in S. cerevisiae by three types of expression vectors: (1) two separate plasmids containing respectively alpha and beta globin genes expressed in diploid strains; (2) a single plasmid comprising alpha and beta globin genes expressed in either haploid or diploid strains; (3) a single plasmid containing …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 10, 1990 and granted September 19, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 10, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 10, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.