Process for iodinating or brominating the alpha-methylenic carbon of a secondary amide
CA 2049882 C · Owner: Shuman, Richard F. · Inventors: Abramson, Newton L.; Karady, Sandor; Shuman, Richard F.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A novel, facile, and specific process for .alpha.-iodinating or .alpha.brominating the .alpha.-methylenic carbon of an azasteroid comprises reacting , the, amide with trialkylsilyl-X (R3Si-X) where X is Br, I, or Cl, and R is methyl ethyl, or n-propyl, in the presence of I2 or Br2. The .alpha.-iodo- or .alpha.bromo-amide, is useful for making the .alpha..beta.-unsaturated amide through dehydrohalogenation.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 26, 1991 and granted January 22, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 26, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 26, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.