Process for producing pentapeptides and intermediates for use in the synthesis
CA 2049004 A1 · Owner: Carlsberg Biotechnology Ltd. A/S · Inventors: Andersen, Anders J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Pentapeptides having the formula H-Asp-Ser-C-Pro-Arg-OH where, Asp, Ser, Pro and Arg may have L- or D-configuration and C denotes, Asp or Asn in L or D configuration are synthesized by reacting , in an aqueous medium Y2-Pro-OH wherein Y2 is a protective, group, with Arg-Ro wherein Ro is OH or is as defined below for R1 below, to form Y2-Pro-Arg-Ro, which is deprotected if, necessary under conversion to Pro-Arg-R1 wherein R1 is an, enzymatically cleavable .alpha.-carboxy substituting group selected from esters, amides, anilides, hydrazides or L-amino acid esters and, thereafter reacting Y3-C(Z3)-OH with Pro-Arg-R1 to form Y3-C(Z3)-Pro-Arg-R1, which is deprotected to C-Pro-Arg-R1 and, then …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 14, 1990. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 14, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 14, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.