3-arylindole and 3-arylindazole derivatives

Abstract From the Canadian patent

3-Arylindole or 3-arylindazole derivatives having formula (see formula I), wherein Ar is optionally substituted phenyl or a heteroaromatic group; R1-R4 are independently selected from hydrogen halogen, alkyl, alkoxy, hydroxy, nitro alkylthio, alkylsulphonyl, alkyl- or dialkylamino cyano, trifluoromethyl, or, trifluoromethylthio; the dotted lines designate optional bonds; X is N or a group CR6 wherein R6 is hydrogen halogen, trifluoromethyl or , alkyl, or X is CH2; Y is N or CH, or Y is C;, R5 is hydrogen cycloalkyl, cycloalkylmethyl, alkyl or alkenyl optionally , substituted, with one or two hydroxy groups or R5 is a group taken from structures 1a and 1b:, (see formula 1a, 1b), wherein n …