Stabilisation of glycosated t-pa
CA 2046876 A1 · Owner: Rudolph, Rainer · Inventors: Rudolph, Rainer; Kohnert, Ulrich
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention concerns a pharmaceutical preparation of a glycosylated protein with t-PA activity with an activity of a least 1.4 MU/ml and a pH value of 4.5 to 9, which contains citrate and at least one compound from the group consisting of a) ascorbic acid, b) EDTA, c) amino compounds of the formula R1R2N - R - X, whereby X = SO3H, H, NH2 or OH R = C1-C9-, alkylene, C3-C6-cycloalkylene or benzylidene and R1 and R2, independently of one another are H, or C1-C3-alkyl, d) guanidinobutyric acid e) dimethylbiguanide, f) 7-aminoheptanoic acid 8-aminooctanoic acid, p-aminomethylbenzoic acid .delta.-aminovaleric acid, .gamma.-aminobutyric acid g) glucosamine, fructose, h) pyrimidine nucleosides …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 19, 1990. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 19, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 19, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.