Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors
CA 2042113 C · Owner: American Home Products Corporation · Inventors: Malamas, Michael S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention relates to spiro-isoquinoline-pyrrolidines having the structural formula (I) and their pharmaceutically acceptable salts thereof. (see formula I) wherein R1 and R2 are independently hydrogen alkyl containing 1 to 6 carbon, atoms, halogen lower alkoxy containing 1 to 6 carbon atoms trifluoromethyl, nitro, aryl or aryl(lower alkyl)oxy wherein aryl contains 6 to 10 carbon atoms and, lower alkyl contains 1 to 6 carbon atoms; and R3 is hydrogen alkyl containing, 1 to 6 carbon atoms, lower alkoxy containing 1 to 6 carbon atoms trifluoromethyl, nitro, aryl or aryl(lower alkyl)oxy wherein aryl contains 6 to 10, carbon atoms and lower alkyl contains 1 to 5 carbon atoms. The …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 8, 1991 and granted August 28, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 8, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 8, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.