Glucose isomerases with an altered ph optimum
CA 2033658 C · Owner: Lasters, Ignace · Inventors: Misset, Onno; Lambeir, Anne-Marie Virginie Renee; Van Der Laan, Jan Metske
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for selecting amino acid residues is disclosed which upon replacement will give rise to an enzyme with an altered pH optimum. The method is specific for metalloenzymes which are inactivated at low pH due to the dissociation of the metal ions. The method is based on altering the pK a of the metal coordinating ligands or altering the K sss for the metal binding. New glucose isomerases with an altered pH optimum are provided according to this method. These altered properties enable starch degradation to be performed at lower pH values.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 4, 1991 and granted July 31, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 4, 2011.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 4, 2013.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.