Pyrimidoindole derivatives and processes for preparation thereof

Abstract From the Canadian patent

Compound of the formula:, wherein R1 R2 and R3 are each hydrogen, lower, alkyl lower alkenyl, aryl or ar(lower)alkyl, R4 is imidazolyl which may have suitable substituent(s) or pyridyl, A is lower alkylene and, ---- is single bond or double bond and pharma-, ceutically acceptable salts thereof. The preparation of these compounds, pharmaceutical compositions containing them and their use as a medicament are also disclosed. These compounds are useful for treating or preventing 5-hydroxytryptamine mediated diseases, for example, central nervous system (CNS) disorders such as psychosis (e.g. schizophrenia mania, etc.), anxiety, and depression; pains or aches such as headaches (e.g. migraine …