Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same

Abstract From the Canadian patent

There are described compounds of the, formula: (see formula I), wherein R1 is aryl which may be substituted with substituent(s) selected from the group consisting of lower alkyl, halogen, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl hydroxy, lower alkylsulfonyloxy, nitro amino, lower alkylamino, acylamino and lower alkyl(acyl)amino; or a heterocyclic group; R2 is hydrogen; methyl substituted with amino, lower aklylamino halogen or acyloxy; acyl; acylamino; cyano; halogen; lower alkylthio; lower alkylsufinyl; or a heterocyclic group; and R3 is aryl substituted with lower alkyl, lower alkylthio, lower alkylsulfinyl halogen, amino, lower alkylamino, acylamino lower, …