4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, process for their preparation, their use as pharmaceuticals, and pharmaceutical preparations and precursors

Abstract From the Canadian patent

1-, 4-Hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters process for their preparation, their use as pharmaceuticals, and pharmaceutical preparations and precursors compounds of the formula I, and the corresponding open-chain dihydroxycarboxylic acids of the formula II, in which X, Y R1, R2, R3, R4 and R5 have the meanings indicated, and also their pharmacologically tolerable salts with bases and their pharmacologically tolerable esters, processes for the preparation of these compounds their use as pharmaceuticals and pharmaceutical preparations are described. In addition, compounds of the formula III, -2-, in which R1, R2, R3, R4 R5, …