1-(pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments

Abstract From the Canadian patent

This invention relates to, 1-(pyridinylamino)-2-pyrrolidinones of the formula (see formula I), wherein R1, R2 and R3 are independently hydrogen loweralkyl, aryl, arylloweralkyl or heteroarylloweralkyl selected from the group consisting of pyridinylmethyl pyridinylethyl, thienylmethyl, thienylethyl or R2 and R3 together form a cycloalkane ring of 4 to 6 carbons or a spiro-fused aryl or heteroaryl cycloalkane; X is halogen, hydroxy loweralky, loweralkoxy, nitro, amino or trifluoromethyl; m is zero or an integer of 1 to 3, the pharmaceutically acceptable acid addition salts thereof and where appropriate the geometrical, optical and stereoisomers and racemic mixtures thereof. The compounds of …