The thermo-inducible expression of heterologous genes in bacillus subtilis and means and methods for its achievement
CA 2022135 A1 · Owner: Cosmina Paola · Inventors: Velati Bellini, Ada; Cosmina Paola; Grandi Guido
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The regulation of the expression of a heterologous gene which codes for a protein of interest in B.subtilis is achieved by the introduction into the microorganism of a plasmid vector containing the gene placed under the control of a strong promoter whose activity is modulated by means of a variation in the temperature by the heat-sensitive repressor of the lambda phage of E.coli. The method enables various heterologous proteins to be synthesised by the culture of strains of B.subtilis with transformations induced by variations in temperature.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 27, 1990. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 27, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 27, 2012.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.