Process for removing bacterial endotoxin from gram-negative polysaccharides
CA 2018709 C · Owner: Merck Sharp & Dohme Corp. · Inventors: Sitrin, Robert D.; Scattergood, Edgar M.; Rienstra, Mark S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for removing endotoxin from, Gram-negative polysaccharides such as polyribosylribitol phosphate by solubilizing polysaccharide-containing powder derived from Gram-negative bacteria fermentation broth to provide a divalent counter ion for endotoxin and adding alcohol incrementally to induce lipopolysaccharide precipition, and mixing material resulting from the alcohol addition with a nonionic resin a detergent, and a chelating agent. A process for removing endotoxin from Gram-negative polysaccharides such as H. influenzae polyribosylribitol phosphate by mixing with a nonionic resin, a detergent and a chelating agent. A process for removing endotoxin from Gram-negative …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 11, 1990 and granted December 26, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended June 11, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 11, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.