Production of modified pe40
CA 2012732 C · Owner: Riemen, Mark W. · Inventors: Stirdivant, Steven M.; Riemen, Mark W.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides modifications of the PE40 domain which eliminate the chemical ambiguities caused by the cysteines in PE40. Substitution of other amino acids such as e.g. alanine for the cysteine residues in PE40 or, deletion of two or more of the cysteine residues improves the biological and chemical properties of conjugates formed between modified PE40 and a targeting agent.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 21, 1990 and granted September 14, 1999. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 21, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 21, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.