Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
CA 2012480 C · Owner: Pettit, George R. · Inventors: Kamano, Yoshiaki; Pettit, George R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A new cytostatic depsipeptide, designated "dolastatin 15" was, isolated from the Indian Ocean shell-like mollusk Dolabella auricularia. Dolastatin 15 inhibited growth of the PS leukemia with ED50 0.0024 µg/mL. Pharmaceutical preparations and therapeutic regimens utilizing Dolastatin 15 its synthetic, counterpart and pharmaceutically active derivatives are disclosed. Dolastatin 15 has the structural formula: (see above formula)
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 19, 1990 and granted May 2, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 19, 2010.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 19, 2012.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.