2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same

Abstract From the Canadian patent

The present invention is directed to, 2-(1-piperazinyl)-4-phenyl-cycloalkano-pyridine derivatives of the formula (I):, (see fig. I), wherein n is 3 4, 5, 6 or 7; R1 is hydrogen atom, C1-C10 alkyl C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl C3-C6 cycloalkyl-(C1-C4), alkyl, hydroxy-(C2-c6) alkyl C1-C3 alkoxy-(C2-C6), alkyl, acyloxy (C2-C6) alkyl unsubstituted or substituted, aroyl-(C1-C6) alkyl unsubstituted or substituted aryl, heteroaryl or acyl; R2 and R3 are the same or different and each represent hydrogen atom, halogen atom C1-C6, alkyl, C1-C6 alkoxy, trifluoromethyl or hydroxy; R4, R5 and R6 are the same or different and each represent hydrogen atom, C1-C6 alkyl, or phenyl, or two …