Diaryl-substituted heterocyclic compounds, their preparation and drugs and cosmetics obtained therefrom

Abstract From the Canadian patent

Compounds of formulae (I) and (Ia):, (see above formulas I II), where L is a saturated or unsaturated five-membered or six-membered heterocyclic structure. The novel compounds and their physiologically tolerated salts can be used in the topical and systemic therapy and prophylaxis of precancerous conditions and carcinomas of the skin, of the mucus membranes and of the internal organs and in the topical and systemic therapy of acne, psoriasis and other dermatological disorders accompanied by pathological changes in hornification in particular, ichthyosis, Darier's disease lichen or leucoplakia, or even, against eczema vitiligo, dry eyes and other corneo-pathias and for the treatment of …