Monoclonal antibody against protein c
CA 2006684 C · Owner: Oklahoma Medical Research Foundation · Inventors: Esmon, Charles T.; Esmon, Naomi L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A Ca+ dependent monoclonal antibody that specifically binds to a specific twelve peptide sequence (E D Q V D P R L I D G K) in the activation region of the Protein C. The antibody does not bind to Activated Protein C and can be used to inhibit activation of Protein C by thrombin-thrombomodulin. The antibody can be isolated from cell culture or ascites fluid in large quantities by affinity chromatography with mild conditions using the peptide bound to an immobilized substrate. The antibody has a number of specific uses in isolation and characterization of Protein C and as a model for the design of Ca+ dependent antibodies for the isolation of other proteins, as a diagnostic and as a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 27, 1989 and granted December 17, 1996. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 27, 2009.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 27, 2011.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.