Derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines as inhibitors of interleukin-1 production
CA 2005196 A1 · Owner: Pfizer Inc. · Inventors: Walker, Frederick J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention relates to the use of certain derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines of the formula and the pharmaceutically-acceptable salts thereof wherein R1 is H, or CH3; R2 is CH3; R3 is (C3-C15) straight chain alkyl or (C7-C20)phenylalkyl which may be substituted in the phenyl by one or two fluoro or chloro substituents; and R4 is H or CH3 to inhibit interleukin-1 production in a mammal. This invention also relates to the use of such compounds for treating interleukin-1 mediated disorders and dysfunctions such as bone and connective tissue metabolism disorders and immune dysfunction in a mammal. The invention further relates pharmaceutical compositions adapted for …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 12, 1989. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 12, 2009.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 12, 2011.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.