Extraction methods for preparing thromboplastin reagents
CA 2002208 C · Owner: Baxter Diagnostics Inc. · Inventors: Maynard, James R.; Hawkins, Pamela L. H.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The Prothrombin Time (PT) is used as a screening test for blood coagulation factor deficiencies and for monitoring oral anti-coagulant therapy using coumadin. Thromboplastin reagents activate the extrinsic pathway of coagulation and are the basis for the Prothrombin Time (PT) test. This invention describes the use of barium sulfate and chaotropic agents and nonionic, detergents, for the extraction of sensitive thromboplastin reagents from tissue. Extraction with sodium thiocyanate alone also greatly enhances thromboplastin sensitivity. This invention should be useful for all thromboplastins and will improve their sensitivity for all PT-based tests and specific assays.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 3, 1989 and granted February 24, 1998. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended November 3, 2009.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 3, 2011.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.