Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same

Abstract From the Canadian patent

Compounds of formula (1) are provided which are useful as Class III type antiarrythmic agents improving cardiac dysfunction, cardiac insufficiency and provide positive inotropic action. The compounds of this invention are embodied by formula (1). (see fig.I) in which A represents -(CH2)m-, -B-(CH2)k- -D-(CH2)1-, (see fig.II) or (see fig.III); B represents an oxygen or a sulfur atom (see fig.IV), (see fig V), or (see fig. VI); D represents (see fig.VII), (see fig. VIII) or (see fig.IX); R1 and R2 each independently represent a hydrogen atom a, lower alkyloxycarbonyl group, an unsaturated lower alkyl group or a lower alkyl group, any one of the hydrogen atoms of said alkyl groups may be …