Method and composition for preventing growth and replication of cancer cells that express the core structure of a mucin-type glycoprotein

Abstract From the Canadian patent

A method of preventing growth and replication of cancer cells that express the core structure of a mucin-type glycoprotein comprising inducing an anti-cancer cell immune response by administering to a subject a vaccine comprising: (a) a pharmaceutically effective amount of an antigen comprising a purified mucin-type glycoprotein carrying Tn or sialyl-Tn epitope, a purified core structure of a mucin-type glycoprotein or a chemically synthesized carbohydrate component linked to a carrier molecule and which are capable of inducing an immune response against the mucin-type glycoprotein, and (b) a pharmaceutically acceptable carrier diluent or excipient.